Launching or scaling a clear aligner brand depends fundamentally on selecting the right OEM partner, who serves as the clinical and operational backbone of the business. This article presents a comprehensive eight-point evaluation framework for choosing an OEM clear aligner partner. The criteria are: (1) treatment planning capability, which accounts for 60% of clinical success per the 60/20/20 rule and demands genuine orthodontic expertise for moderate and complex cases; (2) software platform, requiring AI-powered neural network planning, cloud-native architecture for seamless collaboration, and CBCT integration for anatomically sound tooth movement; (3) material quality, benchmarked against the three-layer standard for comfort, force delivery, and durability; (4) production capacity, automation, and quality consistency to support scalable growth; (5) regulatory compliance, including CE marking, FDA clearance, and ISO 13485 certification; (6) branding flexibility and white-label control, encompassing custom aligner specifications, packaging, and IP ownership of treatment plans; (7) clinical support and training, including real-time assistance and refinement turnaround; and (8) commercial terms and partnership structure, examining total cost of ownership beyond per-unit pricing. The article concludes that the right partner is not merely a vendor but a strategic foundation for brand reputation and long-term clinical success.